规格: | 1mg | 产品价格: | 4500.00 |
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规格: | 5mg | 产品价格: | 18015.00 |
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Catalog Number H-5908
Synonyms NPW-23 (human)
Molecular Formula C₁₁₉H₁₈₃N₃₅O₂₈S
Relative Molecular Mass 2584.05
CAS Registry Number [383415-79-0] net
One Letter Code WYKHVASPRYHTVGRAAGLLMGL
Source Synthetic
Storage Conditions -20 ± 5 °C
Areas of Interest Obesity Research|Pituitary & Hypothalamic Hormones
产品描述
Neuropeptide W-23 (human) is an endogenous ligand of the G-protein-coupled receptors GPR7 and GPR8. It dose-dependently inhibited cAMP accumulation induced by forskolin in CHO-GPR7 and CHO-GPR8 cells, with IC₅₀ values of 0.025 and 0.178 nM, respectively. Intracerebroventricular administration of neuropeptide W-23 (human) in rats increased food intake and stimulated prolactin release.
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温馨提示:不可用于临床ZL。