Lymphocyte-Activation Gene 3 (LAG3) 抗体

Lymphocyte-Activation Gene 3 (LAG3) 抗体抗原    
Lymphocyte-Activation Gene 3 (LAG3)
别名     CD223, LAG-3, Ly66
适用    
 其他选择 小鼠
宿主    
 其他选择 大鼠
克隆类型 (克隆位点)    
单克隆 (C9B7W)
标记    
 其他选择 非结合性
应用范围    
 其他选择 流式细胞分析技术（FACS）
Pubmed     2个引用可参考
规格     0.1 mg
发货至     ZG (更改)
发货时间     29至35个工作日
产品编号 yb120324
产品细节 Lymphocyte-Activation Gene 3 (LAG3) 抗体
免疫原     Murine CD223 Ig fusion protein. Cells from immunised Lewis rats were fused with cells of the Sp/20 myeloma cell line.
克隆位点     C9B7W
亚型     IgG1
特异性     This antibody recognises lymphocyte activation gene-3 (LAG-3), that is also referred to as CD223. Clone C9B7W recognises an epitope within the D2 domain of CD223. The antibody is reported to block the in vitro function of murine LAG-3 but studies suggest that the antibody does not block binding of LAG-3 to MHC class II. We recommend the use of SM2268LE for this purpose.
纯化方法     Affinity chromatography on Protein G
目标详细情况Lymphocyte-Activation Gene 3 (LAG3) 抗体
别名     CD223 / LAG3
背景     CD223 is a 70kD activation-induced cell surface molecule. Murine CD223 is expressed on activated CD4 positive and CD8 positive alpha/beta T lymphocytes and a subset of natural killer (NK) cells. CD223 binds to MHC class II molecules with high affinity and is reported to negatively regulate T cell homeostasis and T cell expansion.Synonyms: FDC, LAG-3, Lymphocyte activation gene 3 protein
基因ID    16768
NCBI登录号    NP_032505
UniProt    Q61790
研究领域     CD Antigens, Surface Receptors of Immune Cells
使用细节Lymphocyte-Activation Gene 3 (LAG3) 抗体
应用备注     Flow Cytometry: 1/50 - 1/200, Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. 
Other applications not tested. 
Optimal dilutions are dependent on conditions and should be determined by the user.
限制     仅限研究用
贮存及处理 Lymphocyte-Activation Gene 3 (LAG3) 抗体
浓度     1.0 mg/mL
缓冲液     PBS, pH 7.4 containing 0.09 % Sodium Azide
储存液     Sodium azide
注意事项     This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项     Avoid repeated freezing and thawing.
储存条件     4 °C/-20 °C
储存方法     Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.