Neuropilin 2 / NRP2抗体

Neuropilin 2 / NRP2抗体产品信息

免疫原 :    
Recombinant Human Neuropilin 2 / NRP2 protein (Catalog#10695-H08H)
Reagents :    PE-conjugated mouse monoclonal antibody
Clone ID :
03
抗体宿主 :    
Mouse IgG1
Concentration :    
20 μl/Test, 0.1 mg/ml
缓冲液 :    Aqueous solution containing 0.5% BSA and 0.09% sodium azide
制备方法 :    
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Neuropilin 2 / NRP2 (rh Neuropilin 2 / NRP2; Catalog#10695-H08H; NP_003863.2; Met 1-Tyr 855) and conjugated with PE under optimum conditions, the unreacted PE was removed.
Neuropilin 2 / NRP2抗体Background
Neuropilin-2 (NRP-2) which is related to NRP-1, is a type I transmembrane glycoprotein and has the structure characteristic with five main extracellular domains: two complement binding (CUB) domains, two coagulation factor V/VIII homology domains, and a MAM (meprin, tyrosine phosphatase domain) region. NRP-2 is a receptor capable of binding two disparate ligands, classⅢ semaphorins (SEMA) and vascular endothelial growth factors (VEGF), and thus regulates two diverse systems by activating cellular signaling pathways via interacting with other cell surface receptors such as VEGF receptors and plexins. NRP-2 is well known for its role in facilitating axonal guidance during the development of the neuronal system, and additionally, it is also expressed in vascular endothelial cells and lymphatic endothelium where it affects proliferation, migration, angiogenesis, as well as formation of small lymphatic vessels and capillaries. Recent study has identified NRP-2 as a polysialylated protein expressed in human dendritic cells and modulates DC-T cell Interactions. Nearly all tumor cells express neuropilins and NRP-2 is predominantly expressed in neuronal tumors and melanomas. Furthermore, it is suggested that as the specific ligand for NRP-2, SEMA 3F inhibits tumor angiogenesis and metastasis.
Neuropilin 2 / NRP2抗体相关产品如下：
hz-1144R    TFPI-2组织因子途径YZ剂-2抗体
hz-0066R    TGF alpha转移生长因子α抗体(TGFα)
hz-0103R    TGF Beta 1转化生长因子β1抗体（TGFβ1）
hz-0100R    TGF beta 2 Propeptide转移生长因子β2抗体（TGFβ2）
hz-0099R    TGF beta 3 propeptide转移生长因子β3抗体（TGFβ3）
hz-0117R    TGF beta Receptor II转移生长因子β受体2抗体（TGF-βRⅡ，TGFβRⅡ）
hz-0638R    TGF beta Receptor I转移生长因子β受体1抗体
hz-0447R    Thyroid peroxidase甲状腺过氧化物酶抗体
hz-1202R    TRADD肿瘤坏死因子受体1相关死亡域蛋白抗体
hz-1217R    TSARG3生精细胞凋亡相关基因3抗体
hz-0339R    T3三碘甲狀腺素T3抗体
hz-0632R    Thioster-containing protein 1按蚊硫酯包含蛋白-1抗体
hz-1909R    Telomerase Binding Protein, P23端粒酶结合蛋白P23抗体
hz-1923R    TSARG6生精细胞凋亡相关基因6抗体
hz-0176R    Trk C酪氨酸激酶C抗体(神经生长因子受体的一种)
hz-1243R    Trop-2原肌球蛋白抗体
hz-0460R    TSHR促甲状腺素受体抗体
hz-0206R    TSHR (CT)促甲状腺素受体抗体（C端）
hz-3439R    Phospho-TAK1(Thr184 + Thr187)磷酸化转化生长因子β活化激酶1
hz-3440R    Phospho-TBK1 (Ser172)磷酸化NF-κB活化激酶抗体
hz-3586R    Tuberin马铃薯球蛋白(结节性硬化)抗体
hz-3441R    Phospho-Tuberin (Ser1387)磷酸化马铃薯球蛋白(结节性硬化)抗体
hz-3442R    Phospho-Tuberin(Ser939)磷酸化马铃薯球蛋白(结节性硬化)抗体
hz-3443R    Phospho-Tuberin(Tyr1571)磷酸化马铃薯球蛋白(结节性硬化)抗体
hz-3444R    Phospho-TSC2 (Thr1462)磷酸化马铃薯球蛋白(结节性硬化)抗体
hz-3445R    Phospho-Tuberin (Thr927)磷酸化马铃薯球蛋白(结节性硬化)抗体
hz-3446R    phospho-Tau protein(Ser396)磷酸化微管相关蛋白抗体
hz-3587R    TNK1非受体型酪氨酸蛋白激酶Tnk1抗体
hz-3450R    Phospho-TNK1 (Tyr277)磷酸化非受体型酪氨酸蛋白激酶Tnk1抗体
hz-3451R    phospho-TOPO II Alpha (Ser1106)磷酸化DNA拓普西异构酶Ⅱ抗体
hz-3588R    TORC1环腺苷酸应答元件结合蛋白转录共激活因子TORC1抗体
hz-3453R    Phospho-Torc1 (Ser151)磷酸化CREB转录共激活因子TORC1抗体
hz-3590R    TORC2CREB转录共激活因子TORC2抗体
hz-0093R    TNF beta肿瘤坏死因子β抗体（TNFβ）
hz-1280R    TCF7L2转录因子7类似物2抗体
hz-0507R    TBX2血栓素B2(一种新发现的抑癌基因)抗体
hz-9734R    TSSK6睾丸特异丝氨酸/苏氨酸激酶6抗体
hz-9735R    TSEN2tRNA剪接内切酶2抗体
hz-9736R    D53肿瘤蛋白D53抗体
hz-7676R    TRAF7肿瘤坏死因子受体相关因子7抗体
hz-6851R    TPST2酪蛋白硫酸转移酶2抗体
hz-7111R    EDA2R肿瘤坏死因子受体超家族成员27抗体