ANPEP / CD13抗体

Mouse ANPEP, also known as Aminopeptidase N and alanyl (membrane) aminopeptidase, is an enzyme that is used as a biomarker to detect damage to the kidneys. ANPEP is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes including macrophages, granulocytes, and synaptic membranes . and is involved in the metabolism of regulatory peptides by diverse cell types. The extracellular carboxyterminal domain of ANPEP contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily,and sequence comparisons with known enzymes of this class show that CD13 and ANPEP are identical. In the nomenclature of CD antigens, this protein has been given the designation CD13. ANPEP can be used to help diagnose certain kidney disorders, since it is found at high levels in the urine when there are kidney problems. Furthermore, defects in this enzyme appear to be a cause of various types of leukemia or lymphoma.
ANPEP / CD13抗体相关产品如下：xy-0398R    Annexin V膜粘连蛋白5抗体
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xy-0059R    APAF1(NT)凋亡蛋白活性因子-1抗体（N端）
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xy-0045M    AGT血管紧张素原抗体
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