TRIB3/p65 interacting inhibitor of NF-kappaB Antibody

 

 TRIB3/p65 interacting inhibitor of NF-kappaB Antibody
 

Cat#：PL0301120
 

Isotype:Rabbit Polyclonal IgG
 

Immunogen：Peptide derived from Hu TRIB3/p65 interacting inhibitor of NF-kappaB.  
 

Purification: Immunogen affinity purified

Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)

Background：

Disrupts insulin signaling by binding directly to Akt kinases and blocking their activation. May bind directly to and mask the 'Thr-308' phosphorylation site in AKT1. Binds to ATF4 and inhibits its transcriptional activation activity. Interacts with the NF-kappa-B transactivator p65 RELA and inhibits its phosphorylation and thus its transcriptional activation activity. Interacts with MAPK kinases and regulates activation of MAP kinases. May play a role in programmed neuronal cell death but does not appear to affect non-neuronal cells. Does not display kinase activity.

Specificity Reaction：Hu, Mo, Rat, Chi, Dog, Pig, Cow, Hor

 

Application Notes:WB: 1:100-500 E: 1:500-1000 IHC: 1:100-500 IF: 1:100-500

 

Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.

 

 

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