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VGF/Nerve growth factor inducible神经生长因子诱导蛋白抗体,抗体质量可靠,订购
VGF/Nerve growth factor inducible神经生长因子诱导蛋白抗体请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称:
神经生长因子诱导蛋白抗体英文名称:
Anti-VGF/Nerve growth factor inducible货号:bs-6349R
抗体来源:兔
克隆类型:多克隆
蛋白分子量:predicted molecular weight: 67kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, mo, rat
测试应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍:VGF is a peptide synthesized and secreted by neurons and is upregulated by NGF in the PC12 cell line. VGF is widely expressed in both the PNS and CNS, but is especially abundant in the adult hypothalamus. VGF plays an essential role in how the brain regulates energy expenditure and body weight. Its expression is rapidly induced by injury, the circadian clock, and neuronal activityFunction : May be involved in the regulation of cell-cell interactions or in synatogenesis during the maturation of the nervous system.NERP peptides are involved in the control of body fluid homeostasis by regulating vasopressin release.Subcellular Location : Secreted. Cytoplasmic vesicle > secretory vesicle. Stored in secretory vesicles and then secreted, NERP peptides colocalize with vasopressin in the storage granules of hypothalamus.Tissue Specificity : Central and peripheral nervous systems, synthesized exclusively in neuronal and neuroendocrine cells.Post-translational modifications : Multiple peptides are derived from VGF, with activities in synaptic plasticity, antidepression, penile erection, autonomic activation, and increases in energy expenditure.