Product Overview
The Stemgent® Dox Inducible Reprogramming Lentivirus Set: Human OKSM provides hOct4, hSox2, hc-Myc, and hKlf4 transcription factors as prepackaged lentivirus particles for inducible reprogramming of human fibroblast cells. The VSV-G pseudotyped lentivirus is capable of infecting both dividing and non-dividing cells. Under the control of the doxycycline (Dox)-inducible tetO operator and in the presence of the reverse tetracycline transcriptional activator (rtTA) and doxycycline, induced expression of hSox2, hOct4, hc-Myc, and hKlf4 has been shown to direct a variety of differentiated cells into induced pluripotent stem (iPS) cells with embryonic stem (ES) cell-like properties.