Xanthine (≥99.5%, HPLC) 黄嘌呤

Product Description

Molecular Formula: C5H4N4O2

Molecular Weight: 152.1

CAS Number: 69-89-6

pKa: 7.7, 11.91

λmax = 277 nm (pH = 10)1

Extinction Coefficient: EmM = 9.3 (pH = 10)1

Xanthine is a catabolic product of purine nucleotide metabolism. It is degraded by xanthine oxidase to uric acid. Natural sources of xanthine or its derivatives include animal organs, yeast, potatoes, coffee beans, and tea.2 Xanthine and xanthine oxidase are used to generate superoxide radicals used to measure the activity of superoxide dismutase.

Precautions and Disclaimer

For Laboratory Use Only. Not for drug, household or other uses.

Preparation Instructions

Xanthine is soluble in sodium hydroxide solutions and in acidic solutions. It is soluble in 1 M NaOH (50 mg/ml), with sonication for less than 5 minutes, yielding a clear solution. It is slightly soluble in water (1 g/14.5 L, 16 °C) and in ethanol.

Storage/Stability

The decomposition of solutions in 0.5 M H2SO4 or in 10 M NaOH is less than 10% after one hour at

100 °C.

Stock solutions of at least 10 mM in sodium hydroxide can be stored at 2-8 °C for one week