N-碘代乙酸基-N-生物素己二胺北京现货

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产品名称：N-碘代乙酸基-N-生物素己二胺
英文名称：Iodoacetyl LC Biotin
产品货号：GS4324
产品规格：50mg

分子量：510.4
储存条件：冷冻（-20℃）

概述

Iodoacetyl-LC-Biotin is long-chain,sulfhydryl-reactive biotinylation reagents.For the reagent,reaction of the iodoacety1 group with a sulfhydryl(-SH)group is rapid and specific,especially when only a slight
reagent-to-sulfhydrylmolar excess is used and the reaction is performed at pH 8.3(7.5-8.5).1-3 The reaction occurs by
nucleophilic substitution of iodine with a thiol(sulfhydryl)group,resulting in a stable thioether bond(Figure 1).If thiols are
unavailable on the molecule,reaction can occur with histidy1 side chains at pH 6.9-7.0,but the reaction must be allowed to
proceed for at least one week.Iodoacetyl reagents also will react with amino groups at pH>10.

应用

Iodoacetyl-LC-Biotin is not soluble in water
and must be dissolved in an organic solvent such as DMF before further dilution in aqueous solutions.

组份

50mg/bottle

技术规格
 

分子式	C18H31IN4O3S
Net Mass Addition	382.53
间隔臂	27.1?
纯度	＞95%on TLC
溶解性	＞2 mg/ml in DMF for subsequent dilution in water or buffer

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