特别声明:本产品及我公司所售其他产品均为科研类试剂产品,严禁用于药物、YL及其他非科研用途。
北京百奥莱博专业生产销*(代"售")重组人PRND(朊蛋白样蛋白doppel) 重组蛋白,我公司供应的分子生物学试剂品类齐全,且具有优势价格,欢迎新老客户垂询订购。
名称:重组人PRND(朊蛋白样蛋白doppel) 重组蛋白
规格:10μg|50μg|500μg|1mg
英文名:Recombinant Human Prion-like protein doppel
产地:国产|进口
品Pai:百奥莱博
编号:JN1290
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Arg27-Gly152在C端含有His标签。
PRND质量控制:>95%(还原性SDS-PAGE)
PRND制剂:液体
PRND保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。
关于PRND:
Prion-like protein doppel is a 152 amino acids protein that belongs to the prion family. The protein encoded by this gene is found on chromosome 20, approximately 20 kbp downstream of the gene encoding cellular prion protein, to which it is biochemically and structurally similar. It is a membrane glycosylphosphatidylinositol-anchored glycoprotein that is found predominantly in testis.Mutations in this gene may lead to neurological disorders.
想要了解更多关于重组人PRND(朊蛋白样蛋白doppel) 重组蛋白的价格、品Pai、厂家、说明书、促销信息,请和我们联*(代"系")。此外我公司还销*(代"售")下面的产品:
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重组人PRND(朊蛋白样蛋白doppel) 重组蛋白关键词:JN1290,重组人PRND,重组人朊蛋白样蛋白doppel,重组PRND,重组人PRND蛋白
·重组人肽基脯*酰顺反异构酶D(PPID)
编号:JN0926
英文名称:Recombinant Human Peptidyl-Prolyl Cis-Trans Isomerase D
规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成,目的基因编码的Met1-Ala370在N端、C端都带有His标签。
PPID质量控制:>95%(还原性SDS-PAGE)
PPID制剂:液体
PPID保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。
关于PPID:
Peptidyl-Prolyl Cis-Trans Isomerase D (PPID) belongs to the cyclophilin-type PPIase family and PPIase D subfamily. PPID is widely expressed and it contains one PPIase cyclophilin-type domain and three TPR repeats. PPID catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerates the folding of proteins. PPID can bind to the immunosuppressant cyclosporine A and is known that its overexpression suppresses the apoptosis in cancer cells.
重组人PRND(朊蛋白样蛋白doppel) 重组蛋白关键词:JN1290,重组人PRND,重组人朊蛋白样蛋白doppel,重组PRND,重组人PRND蛋白
·重组人白介素IL-31(白细胞介素31)
编号:JN0346
英文名称:Recombinant Human Interleukin-31
规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备,目的基因编码的Ser24-Thr164表达纯化而来。
IL-31质量控制:>95%(还原性SDS-PAGE)。
IL-31制剂:冻干品
IL-31保存:
冻干蛋白可在-20℃长期保存,室温也可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天。
复溶后建议分装冻存在-20℃,可保存3个月,应避免反复冻融。
IL-31复溶:
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存,避免反复冻融。
关于IL-31:
Human Interleukin 31 (IL-31) is a cytokine containing a four-helix bundle structure. It shares several structural and functional characteristics with IL-6, Oncostatin M, LIF, and Cardiotrophin-1. Human IL-31 cDNA encodes a 164 amino acid precursor that contains a 23 amino acid signal peptide and a 141 amino acid mature protein. Human and mouse IL-31 share 24% sequence identity in the mature region. IL-31 is mainly associated with activated T cells and is preferentially expressed by type 2 helper T cells (Th2). IL-31 signals via a heterodimeric receptor complex composed of a gp130 related molecule termed IL-31RA (also GPL and GLMR) and an Oncostatin M receptor (OSM Rβ). The IL-31 receptor is constitutively expressed by keratinocytes and upregulated by IFNγ on monocytes. GPL/OSMR signaling is a strong activator of STAT3 and STAT5, and can also activate STAT1, Jak1, and Jak2 signaling pathways. IL-31 regulated immune responses have been implicated in skin physiology and inflammatory skin diseases. Studies have shown that IL31 induces severe pruritis (itching) and dermatitis in transgenic mice.
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