Phospho-Serine Antibody

Description: Affinity purified rabbit polyclonal anti-phosphoserine antibodies, are developed using phosphoserine-KLH conjugates and phosvitin mixture as immunogen. The phosphoserine specific antibodies were affinity purified with serine-phosphorylated peptide immobilized on agarose. This affinity purified antibody showed higher affinity than anti-phosphoserine antibodies from other source Species: Rabbit Formulation: 250 μg/mL antibody stored in PBS, pH 7, with 50% glycerol. Storage & Stability: Store product at – 20℃. Three years from date of shipping. Immunogen: Phosphoserine-KLH and phosvitin mixture Purification: Affinity purified with phosphoserine on agarose Specificity: Recognize proteins phosphorylated on serine residues. No cross-reaction with phosphotyrosine. Tested: human breast cancer tissue, mouse cell, Application(s): ELISA(1:250), WB(1:250), IP(10 μg/mg crude protein), Immunohistochemistry(1:50). Scientific Description: Serine is one of the 20 naturally occurring amino acids. Kinases phosphorylate serine to phosphoserine which is responsible for various signaling processes in eukaryotes. References: Yaffe. M. B. et al. Curr. Opin. Cell. Bio. 2001, 2, 13, 131-138.