简介
The ZytoLight ® porcine X/Y Dual Color Probe is designed for the simultaneous identification and enumeration of porcine sex chromosomes X and Y in interphase cells.
A possible application of this probe is the identification of host and donor cells in porcine homografts in case of sexmismatched organ transplants. Implanted and host cells can be clearly distinguished without distorting the tissue.Additionally, the engraftment success of xenotransplants can be determined as this probe has been shown not to hybridize to human chromosomes.
探针描述
The porcine X/Y Dual Color Probe is a mixture of an orange fluochrome direct labeled probe specific for the porcine ZFX gene region in Xp2.1-2.2 and a green fluochrome direct labeled probe specific for the porcine SRY gene region in Yp1.2-1.3. The porcine X/Y Dual Color Probe does not cross-hybridize to human chromosomes.
结果
In a normal porcine male interphase nucleus, one orange and one green signal are expected. In a normal porcine female interphase nucleus, two orange signals will be observed. Other signal patterns indicate numerical aberrations of sex chromosomes.
采购指南
Z-2094-200 ZytoLight porcine X/Y Dual Color Probe / 20 (200 μl)
相关产品
Z-2028-20 ZytoLight FISH-Tissue Implementation Kit (20)
Incl. Heat Pretreatment Solution Citric, 500 ml; Pepsin Solution, 4 ml; Wash Buffer SSC, 500 ml; 25x Wash Buffer A, 100 ml; DAPI/Antifade-Solution, 0.8 ml