生长因子此类产品包括人、小鼠或大鼠的细胞外蛋白,多数情况下可启始或影响通过细胞表面受体传递的信号。下列产品包括人、小鼠和大鼠的白细胞介素、集落刺激因子、生长因子、干扰素、脂肪因子、BMP蛋白、FGFs、TNFs、可溶性受体、细胞外结合蛋白、非抑制型丝氨酸蛋白酶抑制剂及其他免疫调节蛋白等。
Recombinant Human FGF-basic Peprotech现货直销 产品编号:
100-18B
别名:
Fibroblast Growth Factor-basic, FGF-2, HBGF-2, Prostatropin
描述:
FGF-basic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-basic is a non-glycosylated, heparin-binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland, liver, monocytes, epithelial cells and endothelial cells. FGF-basic signals through FGFR 1b, 1c, 2c, 3c and 4. Recombinant Human FGF-basic is a 17.2 kDa protein consisting of 154 amino acid residues.
氨基酸序列:
AAGSITTLPA LPEDGGSGAF PPGHFKDPKR LYCKNGGFFL RIHPDGRVDG VREKSDPHIK LQLQAEERGV VSIKGVCANR YLAMKEDGRL LASKCVTDEC FFFERLESNN YNTYRSRKYT SWYVALKRTG QYKLGSKTGP GQKAILFLPM SAKS
来源:
E.coli
纯度:
Greater than 95% by SDS-PAGE gel and HPLC analyses.
生物活性:
Assay #1: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 106units/mg.
Assay #2: The ED50 was determined by a cell proliferation assay using balb/c 3T3 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg.
交叉反应:
Cow, Dog, Frog, Hamster, Monkey, Mouse, Pig, Rabbit, Rat, Sheep, Human + Mouse, Rat + Chicken, Human, Horse, Bacteria, Trout, Chicken, Human + Rat, Leech, N/A, Human + Virus, Mouse + Pig
研究领域:
![](http://item.yiqi.com/pic/ConPic/3/ri-angio-cardio.jpg) | 血管生成/ 心血管 | ![](http://item.yiqi.com/pic/ConPic/3/ri-cancer.jpg) | 癌症 |
![](http://item.yiqi.com/pic/ConPic/3/ri-cell_culture.jpg) | 细胞培养 | ![](http://item.yiqi.com/pic/ConPic/3/ri-fgf_superfamily.jpg) | FGF超家族 |
![](http://item.yiqi.com/pic/ConPic/3/ri-inflammation.jpg) | 炎症 | ![](http://item.yiqi.com/pic/ConPic/3/ri-neurobiology.jpg) | 神经生物学 |
![](http://item.yiqi.com/pic/ConPic/3/ri-proliferation.jpg) | 增殖 | ![](http://item.yiqi.com/pic/ConPic/3/ri-stem_cells-differentiation.jpg) | 干细胞及分化 |
![](http://item.yiqi.com/pic/ConPic/3/ri-wound_healing.jpg) | 创伤修复 | |
原产国:
USA