PTEN (phosphatase and tensin homologue deleted on chromosome ten), also referred to as MMAC (mutated in multiple advanced cancers) phosphatase, is a tumor suppressor implicated in a wide variety of human cancers. PTEN encodes a 403 amino acid polypeptide originally described as a dual-specificity protein phosphatase . The main substrates of PTEN are inositol phospholipids generated by the activation of the phosphoinositide 3-kinase (PI3K) . PTEN is a major negative regulator of the PI3K/Akt sign
艾美捷科技有限公司,目前提供Abbkine高质量抗体:磷酸酯酶与张力蛋白同源物 (phospho Ser380) 多克隆抗体,性价比非常高。Abbkine致力于为生命科学研究和YL发展提供的产品和技术。Abbkine设计、开发、生产并销售了一系列独特的产品,包括生命科学领域研究相关的抗体、研究试剂以及细胞功能分析产品。Abbkine的产品为科学研究中的挑战提供卓有成效的解决方案,从而为的科学家节省时间并提高研究效率。作为Abbkine的ZG区域总代理,艾美捷科技有限公司凭借丰富的专业经验,将一如既往的为ZG区域客户提供Abbkine优质的产品和技术服务。
【英文名称】:PTEN (phospho Ser380) Polyclonal Antibody
【中文名称】:磷酸酯酶与张力蛋白同源物 (phospho Ser380) 多克隆抗体
【产品类型】:一抗
【供应商】:Abbkine
【产品货号】:ABP55886
【背景资料】:PTEN (phosphatase and tensin homologue deleted on chromosome ten), also referred to as MMAC (mutated in multiple advanced cancers) phosphatase, is a tumor suppressor implicated in a wide variety of human cancers. PTEN encodes a 403 amino acid polypeptide originally described as a dual-specificity protein phosphatase . The main substrates of PTEN are inositol phospholipids generated by the activation of the phosphoinositide 3-kinase (PI3K) . PTEN is a major negative regulator of the PI3K/Akt signaling pathway . PTEN possesses a carboxy-terminal, noncatalytic regulatory domain with three phosphorylation sites (Ser380, Thr382, and Thr383) that regulate PTEN stability and may affect its biological activity . PTEN regulates p53 protein levels and activity and is involved in G protein-coupled signaling during chemotaxis .蛋白别名为:PTEN; MMAC1; TEP1; Phosphatidylinositol 3; 4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; Mutated in multiple advanced cancers 1; Phosphatase and tensin homolog;基因ID为:5729;蛋白质ID:P60484
【产品规格】:30u/100ul/200ul
【应用类型】:IHC-p,ELISA补充:的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: IHC-p: 1:100-1:300, ELISA: 1:10000. Not yet tested in other applications.
【免疫原】:合成多肽:human PTEN around the phosphorylation site of S380.
【来源宿主】:兔
【反应性】:人,小鼠,大鼠
【保存建议】:厂家推荐蓝冰运输.在发货后能在-20℃保存1年.为限度的避免损失,请在打开管盖之前融化抗体并离心.我们建议使用前分装以避免反复冻融.本产品为液体形式,溶解于PBS缓冲液中,含50%甘油,0.5%BSA和0.02%叠氮化钠.
【产品说明】:点击:磷酸酯酶与张力蛋白同源物 (phospho Ser380) 多克隆抗体查看更详细产品说明,更多应用、储存、价格、货期等信息请致电垂询AbbkineZG区域授权总代理艾美捷科技有限公司。更多特色试剂盒、特色抗体以及特色试剂等产品评论,请点击查看每日生物评论网站。
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