本公司经销DUSP6/MKP-3,双特异性蛋白磷酸酶6/丝裂原活化蛋白激酶磷酸酶3抗体,克隆类型为polyclonal,宿主来源是Rabbit,DUSP6/MKP-3双特异性蛋白磷酸酶6/丝裂原活化蛋白激酶磷酸酶3抗体可应用于WB、elisa、IP、IF、IHC等实验,欢迎垂询订购!
本公司经销DUSP6/MKP-3,双特异性蛋白磷酸酶6/丝裂原活化蛋白激酶磷酸酶3抗体,克隆类型为polyclonal,宿主来源是Rabbit,DUSP6/MKP-3双特异性蛋白磷酸酶6/丝裂原活化蛋白激酶磷酸酶3抗体可应用于WB、elisa、IP、IF、IHC等实验,欢迎垂询订购!
货号:BY-11546R
英文名称:Anti-DUSP6/MKP-3
中文名称:双特异性蛋白磷酸酶6/丝裂原活化蛋白激酶磷酸酶3抗体
其他名称:名Dual specificity phosphatase 6; Dual specificity phosphatase 6 isoform a; Dual specificity protein phosphatase 6; Dual specificity protein phosphatase PYST1; DUS6_HUMAN; DUSP 6; DUSP 6a; Dusp6; DUSP6a; MAP kinase phosphatase 3; Mitogen activated protein kinase phosphatase 3; Mitogen-activated protein kinase phosphatase 3; MKP 3; MKP-3; MKP3; PYST 1; PYST1; Serine/threonine specific protein phosphatase.
抗体来源:Rabbit
克隆类型:polyclonal
蛋白分子量:predicted molecular weight: 42kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, mo, rat, hrs, dog, cow, Rb
产品介绍:Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. The members of the dual-specificity phosphatase protein family include MKP-1/CL100 (3CH134), VHR, PAC1, MKP-2, hVH-3 (B23), hVH-5, MKP-3, MKP-X, and MKP-4. Human MKP-3 maps to chromosome 12q22-q23 and encodes a 381 amino acid protein that specifically inactivates members of the ERK family and is expressed in a variety of tissues with the highest levels in heart and pancreas.Function : Inactivates MAP kinases. Has a specificity for the ERK family.Subcellular Location : Cytoplasm.Similarity : Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.Contains 1 rhodanese domain.Contains 1 tyrosine-protein phosphatase domain.