Anti-IL-28R白细胞介素28受体抗体

本公司经销IL-28R，白细胞介素28受体抗体，克隆类型为polyclonal，宿主来源是Rabbit，IL-28R白细胞介素28受体抗体可应用于WB、elisa、IP、IF、IHC等实验，欢迎垂询订购！

货号：BY-11137R
英文名称：Anti-IL-28R
中文名称：白细胞介素28受体抗体
其他名称：名Alternative namesIFNLR; Class II cytokine receptor CRF2/12; CRF2/12; Cytokine receptor family 2 member 12; IFN lambda R1; IFNLR1; il-28r1; IL28R alpha; Interferon lambda receptor 1; Interferon lambda receptor; Interleukin 28 receptor alpha chain; LICR2; Likely interleukin or cytokine receptor 2.I28RA_HUMAN
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 55kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, dog, pig, cow, Rb
产品介绍：IL-28R is a 535 amino acid protein encoded by the human gene IL28RA. IL-28R belongs to the type II cytokine receptor family ａnd contains 1 fibronectin type-III domain. It is a single-pass type I membrane protein found as a heterodimer with IL-10RB. This is a receptor for a small family of structurally-related cytokines that, like IFNs, are known to induce antiviral activity. The expression of IFN-I （IL-28） mRNA is inducible by viral infection in several cell lines. The receptor complex （IL-28R） that is utilized by all three IFN-l proteins for signaling is composed of two subunits, a receptor designated IL-28R ａnd IL-10R2. Both receptor chains are constitutively expressed on a wide variety of human cell lines ａnd tissues ａnd signal through the Jak-STAT （Janus kinases-signal transducers ａnd activators of transcription） pathway.Function : IL28RA is a class II cytokine receptor that interacts with IL10RB to bind IL28A, IL28B, ａnd IL29, which are related to type I interferons. These ligands play a critical role in response to microbial challenge ａnd activate the JAK/STAT signaling system. It heterodimers with IL10RB. There are 4 isoforms as result of alternative splicing. It is widely expressed. IL28RA belongs to the type II cytokine receptor family, ａnd contains 1 fibronectin type III domain.Subunit : Heterodimer with IL10RB.Subcellular Location : Membrane; Single-pass type I membrane proteinTissue Specificity : Widely expressed.Similarity : Belongs to the type II cytokine receptor family.Contains 1 fibronectin type-III domain.