本公司经销HOXA4,同源盒基因HOXA4蛋白抗体,克隆类型为polyclonal,宿主来源是Rabbit,HOXA4同源盒基因HOXA4蛋白抗体可应用于WB、elisa、IP、IF、IHC等实验,欢迎垂询订购!
本公司经销HOXA4,同源盒基因HOXA4蛋白抗体,克隆类型为polyclonal,宿主来源是Rabbit,HOXA4同源盒基因HOXA4蛋白抗体可应用于WB、elisa、IP、IF、IHC等实验,欢迎垂询订购!
货号:BY-11293R
英文名称:Anti-HOXA4
中文名称:同源盒基因HOXA4蛋白抗体
其他名称:名Dfd like protein;Homeo box A4;Homeobox A4;Homeobox protein Hox-1.4;Homeobox protein Hox-1D;Homeobox protein Hox-A4;Hox 1.4 like protein;hox-1.4;hox-1d;HOX1;HOX1D;HOXA4;HXA4_HUMAN.
抗体来源:Rabbit
克隆类型:polyclonal
蛋白分子量:predicted molecular weight: 34kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, mo, rat
产品介绍:The Hox homeobox genes encode proteins that are transcriptional regulators with an established role in embryonic development. HoxA4 (homeobox A4), also known as HOX1D or HOX1, is a 320 amino acid protein that localizes to the nucleus and contains one homeobox DNA-binding domain. Expressed in the embryonic nervous system, HoxA4 functions as a sequence-specific DNA-binding transcription factor that is part of a regulatory mechanism that provides cells with positional identities during development. Via its ability to bind DNA, HoxA4 plays an important role in the regulation of gene expression, as well as morphogenesis and differentiation. The gene encoding HoxA4 maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Defects in some of the genes localized to chromosome 7 have been linked to Osteogenesis imperfecta, Williams-Beuren syndrome, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.Function : Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Binds to sites in the 5'-flanking sequence of its coding region with various affinities. The consensus sequences of the high and low affinity binding sites are 5'-TAATGA[CG]-3' and 5'-CTAATTTT-3'.Subcellular Location : Nucleus.Tissue Specificity : Embryonic nervous system.Similarity : Belongs to the Antp homeobox family. Deformed subfamily.Contains 1 homeobox DNA-binding domain.