SYP p38/Synaptophysin/SAP-1突触素抗体/突触相关蛋白-1

本公司经销SYP p38/Synaptophysin/SAP-1，突触素抗体/突触相关蛋白-1，克隆类型为polyclonal，宿主来源是Rabbit，SYP p38/Synaptophysin/SAP-1突触素抗体/突触相关蛋白-1可应用于WB、elisa、IP、IF、IHC等实验，欢迎垂询订购！

货号：BY-0121R
英文名称：Anti-SYP p38/Synaptophysin/SAP-1
中文名称：突触素抗体/突触相关蛋白-1
其他名称：名Major synaptic vesicle protein P38; Syn p38; Synaptophysin; SYP; SYPH; SYPH_HUMAN; SypI; Synapse associated protein-1; synapse-associated protein 1-like; 2010110O17Rik; AW011796; DKFZp686K221; FLJ14495; FLJ44185; MGC94115; PRO3113; SYAP1.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 40kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, dog, cow, chk, hrs, pig
产品介绍：Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term ａnd long-term synaptic plasticity.Involvement in disease:Defects in SYP are the cause of mental retardation X-linked SYP-related （MRXSYP） . Mental retardation is characterized by significantly below average general intellectual functioning associated with impairments in adaptative behavior ａnd manifested during the developmental period.Subcellular Location : Cytoplasmic vesicle > secretory vesicle > synaptic vesicle membrane. Cell junction > synapse > synaptosome.Tissue Specificity : Characteristic of a type of small （30-80 nm） neurosecretory vesicles, including presynaptic vesicles, but also vesicles of various neuroendocrine cells of both neuronal ａnd epithelial phenotype.Similarity : Contains 1 BSD domain.突触素SAP-1/SYP（Synaptophysin, FRG-4）是分布于突触囊泡膜上含量丰富的糖蛋白之一，与递质释放关系密切，并可影响突触可塑性。突触相关蛋白-1可作为神经元和神经内分泌细胞的可靠标记物用于神经系统形态、功能和发育以及相关疾病的研究。对于SAP-1的功能及其具体作用机制，尚待进一步研究。产品图片Tissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed ａnd paraffin-embedded; Antigen retrieval: citrate buffer （ 0.01M, pH 6.0 ）, Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer （normal goat serum,C-0005） at 37℃ for 20 min; Incubation: Anti-SYP p38/Synaptophysin/SAP-1 Polyclonal Antibody, Unconjugated（bs-0121R） 1:200, overnight at 4°C, followed by conjugation to the secondary antibody（SP-0023） ａnd DAB（C-0010） stainingAntigen: bs-0121P, 0.2ug/100ul Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000; Secondary: HRP conjugated Goat-Anti-Rabbit IgG（bs-0295G-HRP） at 1: 5000; TMB（C-0024） staining; Read the data in MicroplateReader by 450nm.