本公司经销VAMP1/Synaptobrevin-1,VAMP1囊泡相关膜蛋白1抗体,克隆类型为polyclonal,宿主来源是Rabbit,VAMP1/Synaptobrevin-1VAMP1囊泡相关膜蛋白1抗体可应用于WB、elisa、IP、IF、IHC等实验,欢迎垂询订购!
本公司经销VAMP1/Synaptobrevin-1,VAMP1囊泡相关膜蛋白1抗体,克隆类型为polyclonal,宿主来源是Rabbit,VAMP1/Synaptobrevin-1VAMP1囊泡相关膜蛋白1抗体可应用于WB、elisa、IP、IF、IHC等实验,欢迎垂询订购!
货号:BY-1950R
英文名称:Anti-VAMP1/Synaptobrevin-1
中文名称:VAMP1囊泡相关膜蛋白1抗体
其他名称:名Vesicle Associated Membrane Protein 1; DKFZp686H12131; SYB 1; SYB1; Synaptobrevin 1; Synaptobrevin1; VAMP 1; VAMP-1; Vesicle associated membrane protein 1; Vesicle associated membrane protein 1 synaptobrevin 1.
抗体来源:Rabbit
克隆类型:polyclonal
蛋白分子量:predicted molecular weight: 13kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, mo, rat, hrs, cow, pig, dog, Gpig, Rb, chk
产品介绍:The Vesicle Associated Membrane Proteins (VAMP) or synaptobrevins are calcium binding proteins specific to eukaryotes. VAMPs, along with synaptosomal associated protein of 25 kDa (SNAP-25) and syntaxin, form the core complex of soluble NSF attachment protein receptor (SNARE) proteins that interact with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) and alpha-SNAP. These membrane associated proteins play a key role in the regulation of vesicle membrane fusion with the plasma membrane. The Clostridium tetani neurotoxin is a metalloprotease with specificity for VAMP. In Alzheimer's disease, VAMP levels of all isoforms appear to be significantly lowered. It has been shown that the extreme carboxy-terminus of VAMP1 is involved in subcellular vesicle targeting.Function : Involved in the targeting and/or fusion of transport vesicles to their target membrane.Subcellular Location : Mitochondrion outer membrane; Cytoplasmic vesicle > secretory vesicle > synaptic vesicle membrane. Cell junction > synapse > synaptosome and Cytoplasmic vesicle membrane. Cell junction > synapse > synaptosome.Tissue Specificity : Nervous system, skeletal muscle and adipose tissue.Similarity : Belongs to the synaptobrevin family.Contains 1 v-SNARE coiled-coil homology domain.