p70 S6 kinase alpha磷酸化核糖体p70 S6蛋白激酶抗体

本公司经销p70 S6 kinase alpha，磷酸化核糖体p70 S6蛋白激酶抗体，克隆类型为polyclonal，宿主来源是Rabbit，p70 S6 kinase alpha磷酸化核糖体p70 S6蛋白激酶抗体可应用于WB、elisa、IP、IF、IHC等实验，欢迎垂询订购！

货号：BY-6370R
英文名称：Anti-p70 S6 kinase alpha
中文名称：磷酸化核糖体p70 S6蛋白激酶抗体
其他名称：名p70 S6K alpha; p70（S6K） alpha; p70-beta 1; p70-S6KA; p70S6Ka; Ribosomal protein S6 kinase 70kDa; p70 S6 kinase alpha.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 70kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, cow, pig, hrs, dog, chk, Rb
产品介绍：In studies to elucidate key regulatory pathways in signal transduction, several protein serine/threonine （Ser/Thr） kinases have been identified. Included among such kinases are two distinct families of 40S ribosomal protein S6 Ser/Thr kinases present in somatic animal cells, designated p70 S6 kinase ａnd p90 Rsk kinase. p90 Rsk kinase is maximally activated within minutes of addition of growth factors or phorbol ester to cultured cells followed by activation of p70 S6 kinase. Both enzymes are regulated by serine/threonine phosphorylation, suggesting that specific kinases may exist upstream in the signaling pathway that regulate these kinases. In fact, evidence suggests that one such family of activating enzymes includes the members of the ERK MAP kinase family. The ERK MAP kinases are, in turn, regulated by phosphorylation at threonine ａnd tyrosine residues by a protein kinase designated MEK.Subunit : Interacts with PPP1R9A/neurabin-1.Subcellular Location : Cell junction, synapse, synaptosome. Mitochondrion outer membrane. Isoform Alpha I: Nucleus. Cytoplasm. Isoform Alpha II: Cytoplasm.Tissue Specificity : Widely expressed.Similarity : Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.Contains 1 AGC-kinase C-terminal domain.Contains 1 protein kinase domain.