E019 Enramycin B, EvoPure/恩拉霉素B, EvoPure

Enramycin B, EvoPure/恩拉霉素B, EvoPure
产品编号：E019 
产品规格：10mg

CAS Number	34304-21-7
Molecular Formula	C108H140CI2N26O31
Molecular Weight	2369 g/mol
Form	Powder
Purity Level	≥85.0%
Solubility	Acids (Dilute HCl): Freely soluble Dimethylformamide: Freely soluble Water: Slightly soluble
Storage Conditions	2-8 °C

Description
Enramycin (also known as Enduracidin and Enradin) is a polypeptide antibiotic produced by Streptomyces fungicidusand developed as a food additive in Japan. Enramycin is slightly soluble in water and freely soluble in dilute HCl solution. Enramycin is composed of two different compounds: enramycin A and enramycin B.
TOKU-E offers three forms of enramycin: enramycin (E006), enramycin A, EvoPure? (E018), and enramycin B, EvoPure? (E019). EvoPure? products are single antibiotic fractions, most >99% pure.
Mechanism
Enramycin acts as a MurG inhibitor involved peptidoglycan synthesis in gram positive bacteria. MurG catalyzes the transglycosylation reaction in the last step of peptidoglycan biosynthesis. Inhibition of this step greatly compromises cell wall integrity leading to cell death by lysis.
Spectrum
Enramycin has a strong antibacterial activity against Gram-positive bacteria and inhibits development of major gut flora pathogens.  Resistance or cross-resistance with existing antibiotics has rarely been observed.