Human CD27 Ligand / CD70 Protein, His,Flag Tag (active trimer) (MALS verified)

内毒素:
Less than 1.0 EU per μg by the LAL method.

纯度:
>95% as determined by SDS-PAGE.

活性:
Immobilized Human CD27 Ligand, His,Flag Tag (active trimer) (MALS verified) (Cat. No. CDL-H52Da) at 2 μg/mL (100 μL/well) can bind Human CD27, Fc Tag (Cat. No. CD7-H5254) with a linear range of 2-125 ng/mL (QC tested).

产品背景:
Cluster of Differentiation 70 (CD70) is also known as CD27 ligand (CD27L / CD27LG), TNFSF7, TNFSF7G, is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and is a surface antigen found on activated T-and B-lymphocytes and mature dendritic cells. Binding of CD70 to its receptor CD27 induces in priming, effector functions, differentiation and memory formation of T-cells, and thus is invloved in the biological processes including T-cell activation, the proliferation of costimulated T-cells, as well as the generation of cytolytic T-cells. CD70 on T cells provides costimulatory signals that are required for T cell proliferation, clonal expansion and the promotion of effector T cell formation. CD70 on mouse B cell has been shown to inhibit terminal differentiation of activated B cells into plasma cells and enhances commitment to memory B cell responses. CD70 induces proliferation and IFNγ production, on NK cells.

产品描述:

This protein carries a polyhistidine tag at the N-terminus, followed by a flag tag.

The protein has a calculated MW of 49.3 kDa. The protein migrates as 50-60 kDa under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.

SDS-PAGE

 

因为难以在供应系统上进行数据同步，所以了解更多产品规格及产品数据，请移步：

http://www.acrobiosystems.cn/P1804-Human_CD27_Ligand_%7C_CD70_Protein_HisFlag_Tag_active_trimer_MALS_verified.html

订购方式
您可以通过官网查看产品信息、拨打订购电话、发送邮件或者直接点索取报价等方式进行订购，我们的客服将会竭诚为您服务。
电话：400-682-2521  
网址：http://www.acrobiosystems.cn
邮箱：order.cn@acrobiosystems.com（订购及产品咨询）(请咨询时注明是在丁香通看到产品信息）