Human 4-1BB Ligand / TNFSF9 (71-254) Protein, Fc Tag (active trimer) (MALS verified) DS MSDS COA

内毒素:
Less than 1.0 EU per μg by the LAL method.

纯度:
>90% as determined by SDS-PAGE.

活性:
Immobilized Human 4‑1BB, His Tag (Cat. No. 41B-H5227) at 2 μg/mL (100 μL/well) can bind Human 4-1BB Ligand (71-254), Fc Tag (active trimer) (MALS verified) (Cat. No. 41L-H5265) with a linear range of 0.2-10 ng/mL (QC tested).

产品背景:
Tumor necrosis factor ligand superfamily member 9 (4-1BBL) is also known as 4-1BB ligand, CD137L or TNFSF9, which is a cytokine that binds to TNFRSF9. 4-1BBL is the high affinity ligand of 4-1BB. 4-1BBL induces the proliferation of activated peripheral blood T-cells. Also, 4-1BBL may have a role in activation-induced cell death (AICD). Furthermore, 4-1BBL may play a role in cognate interactions between T-cells and B-cells/macrophages. As for diseases, 4-1BBL is involved in cancers, infectious diseases and autoimmune diseases.

产品描述:

This protein carries a human IgG1 Fc tag at the N-terminus.

The protein has a calculated MW of 87.5 kDa. The protein migrates as 130-150 kDa under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.

SDS-PAGE
 

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