FAIM2 / LIFEGUARD Antibody (N-Terminus)

分子量：
35kDa
细胞定位：
Antigen Cellular Localization:Cell membrane; Multi-pass membrane protein. Membrane raft. Cell junction, synapse, postsynaptic cell membrane
形式：
Liquid
参考文献：
Somia N.V.,et al.Proc. Natl. Acad. Sci. U.S.A. 96:12667-12672(1999).Nagase T.,et al.DNA Res. 6:63-70(1999).Ota T.,et al.Nat. Genet. 36:40-45(2004).Scherer S.E.,et al.Nature 440:346-351(2006).Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
产品概述：
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.This product is a high quality FAIM2 / LIFEGUARD antibody (N-Terminus).
功能：
Antiapoptotic protein which protects cells uniquely from Fas-induced apoptosis. Regulates Fas-mediated apoptosis in neurons by interfering with caspase-8 activation. May play a role in cerebellar development by affecting cerebellar size, internal granular layer (IGL) thickness, and Purkinje cell (PC) development.
总结：
Antiapoptotic protein which protects cells uniquely from Fas-induced apoptosis. Regulates Fas-mediated apoptosis in neurons by interfering with caspase-8 activation. May play a role in cerebellar development by affecting cerebellar size, internal granular layer (IGL) thickness, and Purkinje cell (PC) development.
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