分子量:
130kDa
细胞定位:
Antigen Cellular Localization:Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side
形式:
Liquid
参考文献:
Ooi C.E.,et al.EMBO J. 16:4508-4518(1997).Simpson F.,et al.J. Cell Biol. 137:835-845(1997).Totoki Y.,et al.Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.Grimwood J.,et al.Nature 428:529-535(2004).Zhang C.,et al.Submitted (FEB-1999) to the EMBL/GenBank/DDBJ databases.
产品概述:
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.This product is a high quality AP3D1 / Adaptin Delta antibody (aa686-698).
功能:
Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
总结:
Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
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