AP3D1 / Adaptin Delta Antibody (aa686-698) | LBP81849 | Leading Biology

商品分类：多克隆抗体

产品概述：Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

靶点/蛋白：aa 686-698 of Human AP3D1.

来源：Goat

参考文献：Ooi C.E.,et al.EMBO J. 16:4508-4518(1997).Simpson F.,et al.J. Cell Biol. 137:835-845(1997).Totoki Y.,et al.Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.Grimwood J.,et al.Nature 428:529-535(2004).Zhang C.,et al.Submitted (FEB-1999) to the EMBL/GenBank/DDBJ databases.

特异性：Human, Chicken

别名：AP-3 complex subunit delta-1, AP-3 complex subunit delta, Adaptor-related protein complex 3 subunit delta-1, Delta-adaptin, AP3D1

应用：ELISA (1:5000-1:20000), IHC-P (2.5 μg/ml), WB (1:500-1:2000)

简单描述：Goat Polyclonal AP3D1 / Adaptin Delta Antibody (aa686-698). Validated for use in WB, IHC-P, E.

详情：FunctionPart of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.Cellular_LocationCytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic sideTissue_LocationPresent in all adult tissues examined with the highest levels in skeletal muscle, heart, pancreas and testis

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