CD79a Antibody, clone ZL7-4 (Monoclonal Antibody) (FITC) | LM11721 | Leading Biology

商品分类：单克隆抗体

靶点/蛋白：Mouse anti-Human CD79a antibody, clone ZL7-4 recognizes ?the human B-cell antigen receptor complex-associated protein alpha chain, also known as MB-1 membrane glycoprotein or CD79a. clone ZL7-4 reacts with CD79a positive cells by flow cytometry and with CD79a in an ELISA specific for a fusion protein of CD79a-Fc.Mouse anti-Human CD79a antibody, clone ZL7-4 has been reported to be useful in distinguishing B-CLL from mantle cell lymphoma in flow cytometric assays (Bellet al.1999).Mouse anti-Human CD79a antibody, clone ZL7-4 has been reported to be suitable for Immunohistochemistry on frozen and pre-treated paraffin sections, but does exhibit epithelial staining.Mouse anti-Human CD79a antibody, clone ZL7-4 has been reported to induce phosphorylation of syk kinase ?(Lanhamet al.2003).

来源：Mouse

参考文献：1. Zhang. L. et al. (1995) The development of anti-CD79 monoclonal antibodies for treatment of B-cell neoplastic disease. Therapeutic Immunology 2:191-202 2. Bell, P.B. et al. (1999) CD79a detected by ZL7.4 separates chronic lymphocytic leukemia from mantle cell lymphoma in the leukemic phase Cytometry (Comm. Clin. Cytometry) 38: 102 - 105. 3. Lanham, S. et al. (2003) Differential signaling via surface IgM is associated with VH gene mutational status and CD38 expression in chronic lymphocytic leukemiaBlood. 101: 1087 - 1093. 4. Vendel,A.C. et al (2009) B and T lymphocyte attenuator regulates B cell receptor signaling by targeting Syk and BLNKJ Immunol. 182: 1509-17. 5. Allsup, D.J. et al. (2005) B-cell receptor translocation to lipid rafts and associated signaling differ between prognostically important subgroups of chronic lymphocytic leukemia.Cancer Res. 65: 7328-37. 6. Cragg, M.S. et al. (2002) The alternative transcript of CD79b is overexpressed in B-CLL and inhibits signaling for apoptosis.Blood. 100: 3068-76. 7. Rahemtullah, A. et al. (2008) CD20+ T-cell lymphoma: clinicopathologic analysis of 9 cases and a review of the literature.Am J Surg Pathol. 32 (11): 1593-607.

特异性：Human

别名：B-cell antigen receptor complex-associated protein alpha chain, Ig-alpha, MB-1 membrane glycoprotein, Membrane-bound immunoglobulin-associated protein, Surface IgM-associated protein, CD79a, CD79A, IGA, MB1

简单描述：Mouse Monoclonal CD79a Antibody, clone ZL7-4 (Monoclonal Antibody) (FITC). Validated for use in FC, E, IP. Clone: ZL7-4.

生物商城：http://www.annoron.com

办公电话：010-56256916

官方售后：400-965-8633

企业 QQ：3212874516、3198592576

地 址：北京大兴经济技术开发区(亦庄)同济中路7号兴盛国际A栋4层