Semaphorin 3E (internal) Antibody (internal region)

分子量：
89228 Da
细胞定位：
Antigen Cellular Localization:Secreted.
形式：
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
参考文献：
Semaphorin 3E and plexin-D1 control vascular pattern independently of neuropilins. Gu C, Yoshida Y, Livet J, Reimert DV, Mann F, Merte J, Henderson CE, Jessell TM, Kolodkin AL, Ginty DD. Science. 2005 Jan 14;307(5707):265-8. Epub 2004 Nov 18. PMID: 15550623
产品概述：
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.This product is a high quality Semaphorin 3E (internal) antibody (internal region).
功能：
Plays an important role in signaling via the cell surface receptor PLXND1. Mediates reorganization of the actin cytoskeleton, leading to the retraction of cell projections. Promotes focal adhesion disassembly and inhibits adhesion of endothelial cells to the extracellular matrix. Regulates angiogenesis, both during embryogenesis and after birth. Can down- regulate sprouting angiogenesis. Required for normal vascular patterning during embryogenesis. Plays an important role in ensuring the specificity of synapse formation (By similarity).
总结：
This antibody is expected to recognise both reported isoforms (NP_036563.1; NP_001171600.1).
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