Glycogen-Synthase Antibody (C-term)

分子量：
83786 Da
细胞定位：

形式：
50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
参考文献：
1. Browner, M. F.; Nakano, K.; Bang, A. G.; Fletterick, R. J. : Proc. Nat. Acad. Sci. 86: 1443-1447, 1989.
2. Skurat, A., and Roach, P. J. (1996) in Diabetes Mellitus pp. 213-222.
3. Hardy, T. A., and Roach, P. J. (1993) J. Biol. Chem. 268, 23799-23805
4. Skurat, A. V., Wang, Y. & Roach, P. J. (1994) J. Biol. Chem. 269, 25534

产品概述：
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.This product is a high quality Glycogen-Synthase antibody (C-term).
功能：
Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan.
总结：
Glycogen synthase is an enzyme of the transferase class that catalyses the reaction of UDP-glucose and (1,4-α-D-glucosyl)n to yield UDP and (1,4-α-D-glucosyl)n+1 (1-2). This tetrameric enzyme is the rate-limiting step for glycogen synthesis (3). Glycogen concentrations are regulated by the complementary activities of glycogen phosphorylase and glycogen synthase. Glycogen synthase activity is regulated by phosphorylation of serine residues and by insulin stimulation (4). Glycogen synthase is known to have two forms; the unphosphorylated and most active form, synthase-a, and the phosphorylated glucose-6-phosphate-dependent form, synthase-b.
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