特别提示:包括重组Hirudin在内,本公司的所有产品仅可用于科研实验,严禁用于临床YL及其他非科研用途!
产品名称:重组Hirudin
英文名称:Recombinant Hirudin
产品货号:GS4883
产品规格:2μg
分子量:Approximately 6.7kDa,a single non-glycosylated polypeptide chain containing 63 amino acid residues.
储存条件:冷冻(-20℃)
概述Hirudin is the most potent natural thrombin-specific protease inhibitor,and is originally derived in the salivary glands of the medicinal leech.Unlike heparin,hirudin act directly on thrombin,rather than through other clotting factors.They have a high binding affinity and specificity for thrombin.Therefore,hirudin prevents or dissolves the formation of clots and thrombi,and has therapeutic value in blood coagulation disorders,in the treatment of skin hematomas and of superficial varicose veins,either as an injectable or a topical application cream.
使用说明This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格 外观 | Sterile Filtered White lyophilized(freeze-dried)powder. |
纯度 | >96%by SDS-PAGE and HPLC analyses. |
来源 | Pichia Pastoris |
生物活性 | The biological activity is determined by chromogenic assay,1 unit is defined as the amount of Hirudin that neutralizes 1 unit of the WHO preparation 89/588 of thrombin.The specific activity is no less than 14,000 ATU/mg protein. |
成分 | Lyophilized from a 0.2μmfiltered solution of 20mMPBS,pH 7.0,containing 2%mannitol. |
内毒素 | Less than 1 EU/μg of rHirudin as determined by LAL method. |
复溶 | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions. |
氨基酸序列 | VVYTDCTESG QNLCLCEGSN VCGQGNKCIL GSDGEKNQCV TGEGTPGPQS HNDGDFEEPE EYL |
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温馨提示:不可用于临床ZL。