特别提示:包括重组人FCGR3B在内,本公司的所有产品仅可用于科研实验,严禁用于临床YL及其他非科研用途!
产品名称:重组人FCGR3B
英文名称:Recombinant Human Low Affinity Immunoglobulin Gamma Fc Region Receptor III-B
产品货号:JN1862
产品规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Thr20-Gln208在C端含有Fc标签和His标签
FCGR3B质量控制:>95%(还原性SDS-PAGE)
FCGR3B制剂:冻干品
FCGR3B保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
FCGR3B复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于FCGR3B:
Low affinity immunoglobulin gamma Fc region receptor III-B, also known as Fc-gamma RIII-beta, FcR-10, IgG Fc receptor III-1, FCG3, FCGR3, CD16b and FCGR3B. FCGR3B is a GPI-anchor membrane protein and contains two Ig-like C2 type domains. FCGR3B can be expressed in orphonuclear leukocytes and stimulated eosinophils. FCGR3B can interact with INPP5D/SHIP1. FCGR3B localizes in the FCGR gene cluster is a CN polymorphic gene involved in the recruitment of polymorphonuclear neutrophils to sites of inflammation and their activation. FCGR3B may serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.
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温馨提示:不可用于临床ZL。