CD11b-PerCP-Vio700/CD11b antibodies, human and mouse

品Pai:miltenyi，产品名称：CD11b-PerCP-Vio700, h&m&nhp
CD11b antibodies, human and mouse - Miltenyi Biotec
货号：130-097-585
CD11b, also known as Mac-1 α or integrin αM chain, is part of the CD11b/CD18 heterodimer (Mac-1 α, Mβ2 integrin), also known as the C3 complement receptor. It functions as a receptor for complement (C3bi), fibrinogen, or clotting factor X. In humans, CD11b is strongly expressed on myeloid cells and weakly expressed on NK cells and some activated lymphocytes as well as on microglia in the brain. In mice, the CD11b antigen is expressed on monocytes/macrophages and microglia. To a lower extent it is expressed on granulocytes, NK cells, CD5⁺ B-1 cells, and subsets of dendritic cells. The monoclonal M1/70.15.11.5 antibody recognizes the human, mouse, and non-human primate CD11b antigen.

Alternative namesITGAM, CR3A, Mac-1 α, MAC1A, MO1A, SLEB6, integrin αM

Clone and isotype

Clone	Isotype
M1/70.15.11.5	rat IgG2bκ