CD314(NKG2D)-Biotin/CD314 (NKG2D) antibodies, human

品Pai:miltenyi，产品名称：CD314(NKG2D)-Biotin, human
CD314 (NKG2D) antibodies, human - Miltenyi Biotec
货号：130-092-825
Clone BAT221 recognizes CD314 (NKG2D), a cell surface receptor of the type II transmembrane receptor NKG2 family. It is expressed on NK cells, CD8⁺ α/β T cells, and γ/δ T cells. Though NKG2D itself possesses no intrinsic signaling capability, ligand engagement while associated to the adaptor proteins DAP10 or DAP12 induces cytolytic activation in NK cells as well as costimulation in certain T cell populations. Ligands for NKG2D are stress-inducible MHC Class I-related MICA, MICB, and UL16-binding proteins, expressed predominantly on epithelial cells and numerous carcinomas.

Alternative namesKlrk1, KLR, NKG2D

Clone and isotype

Clone	Isotype
BAT221	mouse IgG1