牛胰岛素/Insulin/胰岛素来源于牛

• 产品编号：I0102
• 中文名称：牛胰岛素/Insulin/胰岛素来源于牛
• 英文名称：Insulin from bovine pancreas
• 英文别名:Insulin
• CAS号:11070-73-8
• 分子式:C254H377N65O75S6
• 分子量:5733.49
• 纯度:≥27units/mg
• EC号:234-291-2
• MDL号:MFCD00131380

含量：≥27 USP units/mg (HPLC)
干燥失重：≤10.0%
性状：白色或类白色的结晶粉末。

用途：生化研究。胰岛素是机体内WY降低血糖的激素，也是WY同时促进糖原、脂肪、蛋白质合成的激素。作用机理属于受体酪氨酸激酶机制。
保存：-20°C

Application
Insulin is used as a growth factor in many mammalian cell culture systems.

Biochem/physiol Actions
Two-chain polypeptide hormone produced by the β-cells of pancreatic islets. Its molecular weight is ~5800 Da. The α and β chains are joined by two interchain disulfide bonds. The α chain contains an intrachain disulfide bond. Insulin regulates the cellular uptake, utilization, and storage of glucose, amino acids, and fatty acids and inhibits the breakdown of glycogen, protein, and fat.

Reconstitution
Insulin has low solubility at neutral pH. It can be solubilized at 2 mg/ml in dilute acetic or hydrochloric acid, pH 2-3.

Physical form
powder-0 °C; solution stable 2-8 °C, 1 year