MIB2 Antibody (N-Term) | LBP84000 | Leading Biology

商品分类：多克隆抗体

产品概述：E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors (By similarity).

靶点/蛋白：This MIB2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 216-249 amino acids from human MIB2.

来源：Rabbit

存储溶液：Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

参考文献：Takeuchi T.,et al.Am. J. Pathol. 163:1395-1404(2003).Takeuchi T.,et al.Submitted (JUN-2002) to the EMBL/GenBank/DDBJ databases.Matsuda A.,et al.Oncogene 22:3307-3318(2003).Ota T.,et al.Nat. Genet. 36:40-45(2004).Gregory S.G.,et al.Nature 441:315-321(2006).

特异性：Mouse

别名：E3 ubiquitin-protein ligase MIB2, 6.3.2.-, Mind bomb homolog 2, Novel zinc finger protein, Novelzin, Putative NF-kappa-B-activating protein 002N, Skeletrophin, Zinc finger ZZ type with ankyrin repeat domain protein 1, MIB2, SKD, ZZANK1

应用：WB~~1:1000

简单描述：Rabbit polyclonal MIB2 Antibody (N-Term). Validated for use in WB, E.

详情：FunctionE3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors (By similarity).Cellular_LocationCytoplasm. Endosome. Note=Colocalizes with endosomal compartmentsTissue_LocationExpressed in skeletal muscle, and to a lesser extent in heart, brain and kidney.

生物商城：http://www.annoron.com

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企业 QQ：3212874516、3198592576

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