SORBS1 / ponsin (internal) Antibody (internal region) | LBP85142 | Leading Biology

商品分类：多克隆抗体

产品概述：This antibody is expected to recognise all 7 reported isoforms (NP_006425.2, NP_056200.1, NP_001030126.1, NP_001030127.1, NP_001030128.1, NP_079267.1 and NP_001030129.1).

来源：Goat

存储溶液：0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin

参考文献：A novel isoform of Cbl-associated protein that binds protein kinase A. Matson SA, Pare GC, Kapiloff MS. Biochim Biophys Acta. 2005 Feb 14;1727(2):145-9. Epub 2004 Dec 28. PMID: 15716063

特异性：' + item.reactivity + '

别名：Sorbin and SH3 domain-containing protein 1, Ponsin, SH3 domain protein 5, SH3P12, c-Cbl-associated protein, CAP, SORBS1 (HGNC:14565)

简单描述：Goat Polyclonal SORBS1 / ponsin (internal) Antibody (internal region). Validated for use in E.

详情：FunctionPlays a role in tyrosine phosphorylation of CBL by linking CBL to the insulin receptor. Required for insulin- stimulated glucose transport. Involved in formation of actin stress fibers and focal adhesions (By similarity).Cellular_LocationCell junction, adherens junction. Cell membrane. Cytoplasm, cytoskeleton. Cell junction, focal adhesion Nucleus. Nucleus matrix Note=Colocalizes with the Ten-1 ICD form of TENM1 in the nucleus (By similarity). Colocalizes with actin stress fibers. Also detected at the plasma membrane and in neuronal intranuclear inclusions. Colocalized with PXN at focal adhesions during myogenic differentiation.Tissue_LocationDetected in skeletal muscle (at protein level). Widely expressed with highest levels in heart and skeletal muscle.

生物商城：http://www.annoron.com

办公电话：010-56256916

官方售后：400-965-8633

企业 QQ：3212874516、3198592576

地 址：北京大兴经济技术开发区(亦庄)同济中路7号兴盛国际A栋4层