商品分类:多克隆抗体
产品概述:Required for the assembly of a functional nuclear pore complex (NPC) on the surface of chromosomes as nuclei form at the end of mitosis. May initiate NPC assembly by binding to chromatin and recruiting the Nup107-160 subcomplex of the NPC. Also required for the localization of the Nup107-160 subcomplex of the NPC to the kinetochore during mitosis and for the completion of cytokinesis.
靶点/蛋白:This antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1210-1260 amino acids from human.
来源:Rabbit
存储溶液:Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
参考文献:Kimura N.,et al.Genes Cells 7:435-446(2002).Lightfoot J.,et al.Submitted (OCT-2002) to the EMBL/GenBank/DDBJ databases.Gregory S.G.,et al.Nature 441:315-321(2006).Bechtel S.,et al.BMC Genomics 8:399-399(2007).Liu B.,et al.Submitted (JUL-1999) to the EMBL/GenBank/DDBJ databases.
特异性:Human
别名:Protein ELYS, Embryonic large molecule derived from yolk sac, Protein MEL-28, Putative AT-hook-containing transcription factor 1, AHCTF1, ELYS, TMBS62
应用:WB~~1:1000
简单描述:Rabbit Polyclonal Human-AHCTF1 (S1232) Antibody. Validated for use in WB, E.
详情:FunctionRequired for the assembly of a functional nuclear pore complex (NPC) on the surface of chromosomes as nuclei form at the end of mitosis. May initiate NPC assembly by binding to chromatin and recruiting the Nup107-160 subcomplex of the NPC. Also required for the localization of the Nup107-160 subcomplex of the NPC to the kinetochore during mitosis and for the completion of cytokinesis.Cellular_LocationCytoplasm. Nucleus matrix. Chromosome, centromere, kinetochore. Nucleus, nucleoplasm. Nucleus, nuclear pore complex. Note=Localizes to the nuclear pore complex (NPC) throughout interphase. Localizes to the kinetochore from prophase, and this appears to require the Nup107- 160 subcomplex of the NPC. Localizes to the periphery of chromatin from late anaphase
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温馨提示:不可用于临床ZL。