TOP2A / Topoisomerase II Alpha Antibody (clone Ki-S1) | LM13146 | Leading Biology

商品分类：单克隆抗体

产品概述：Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation (By similarity).

来源：Mouse

参考文献：Tsai-Pflugfelder M.,et al.Proc. Natl. Acad. Sci. U.S.A. 85:7177-7181(1988).Wasserman R.A.,et al.Cancer Res. 53:3591-3596(1993).Lang A.J.,et al.Gene 221:255-266(1998).Sng J.H.,et al.Biochim. Biophys. Acta 1444:395-406(1999).Zody M.C.,et al.Nature 440:1045-1049(2006).

特异性：Human

别名：DNA topoisomerase 2-alpha, 5.99.1.3, DNA topoisomerase II, alpha isozyme, TOP2A, TOP2

应用：IHC-P (1:50)

简单描述：Mouse Monoclonal TOP2A / Topoisomerase II Alpha Antibody (clone Ki-S1). Validated for use in IHC-P. Clone: Ki-S1.

详情：FunctionControl of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation (By similarity).Cellular_LocationCytoplasm. Nucleus, nucleoplasm. Note=Generally located in the nucleoplasm

生物商城：http://www.annoron.com

办公电话：010-56256916

官方售后：400-965-8633

企业 QQ：3212874516、3198592576

地 址：北京大兴经济技术开发区(亦庄)同济中路7号兴盛国际A栋4层