Cyclin A2 (S- & G2-phase Cyclin) Antibody - Without BSA and Azide | LM10599 | Leading Biology

商品分类：单克隆抗体

产品概述：It recognizes a protein of 54kDa, which is identified as cyclin A. Its epitope is located amino acids 144-148 of human Cyclin A2. Cyclins are regulatory subunits of the cyclin-dependent kinases (cdkā€?s) and they control transition at different specific phases of the cell cycle. The temporal expression of cyclins is tightly regulated and subsequently plays a critical role in controlling the enzymatic activity of cdkā€?s. These cyclin/cdk complexes are essential for passage through specific stages in the cell cycle. In mammalian somatic cells, cyclin A is required for S-phase and passage through G2-phase. The D and E type cyclins regulate the passage of G1, while cyclin B is a critical regulator of mitosis. Mutation or disruption of normal cyclin A expression causes cells to arrest in G2-phase.

来源：Mouse

存储溶液：200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

参考文献：Adamczewski JP; Gannon JV; Hunt T. Simian virus 40 large T antigen associates with cyclin A and p33cdk2. Journal of Virology, 1993, 67(11):6551-7

特异性：Human, Mouse, Cow, African Green Monkey

别名：Cyclin-A2, Cyclin-A, CCNA2, CCN1, CCNA

简单描述：Mouse Monoclonal Cyclin A2 (S- & G2-phase Cyclin) Antibody - Without BSA and Azide. Validated for use in IF, FC. Clone: E67.

详情：FunctionEssential for the control of the cell cycle at the G1/S (start) and the G2/M (mitosis) transitions.Cellular_LocationNucleus. Cytoplasm. Note=Cytoplasmic when associated with SCAPER

生物商城：http://www.annoron.com

办公电话：010-56256916

官方售后：400-965-8633

企业 QQ：3212874516、3198592576

地 址：北京大兴经济技术开发区(亦庄)同济中路7号兴盛国际A栋4层