Biotinylated Human PD-L2 / B7-DC Protein, Fc,Avitag™

内毒素:
Less than 1.0 EU per μg by the LAL method.

纯度:
>95% as determined by reduced SDS-PAGE.

活性:
Measured by its binding ability in a functional ELISA. Immobilized Human PD-1, Fc Tag (Cat. No. PD1-H5257) at 2 μg/mL (100 μL/well) can bind Biotinylated Human PD-L2, Fc,Avitag (Cat. No. PD2-H82F6) with a linear range of 0.5-16 ng/mL (QC tested).

产品背景:
Programmed cell death 1 ligand 2 (PD-L2 or PDCD1 ligand 2) is also known as Butyrophilin B7-DC, CD antigen CD273, which belongs to the immunoglobulin superfamily or BTN/MOG family. The expression of PD-L2 is up-regulated by IFNG/IFN-gamma stimulation in monocytes and induced on dendritic cells grown from peripheral blood mononuclear cells with CSF2 and IL-4. PD-L2 Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PD-L2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.

产品描述:
This protein carries a human IgG1 Fc tag at the C-terminus, followed by a Avi tag (Avitag™). The protein has a calculated MW of 51.0 kDa. The protein migrates as 66-91 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
因为难以在供应系统上进行数据同步//所以了解更多产品规格及产品数据//请移步：
http://www.acrobiosystems.cn/P1125-Biotinylated_Human_PD_L2_%7C_B7_DC_Protein_FcAvitag.html