产品编号:
150-17
别名:
SEMA3A,SEMAD
描述:
Semaphorins are a large group of structurally related secreted, GPI-anchored and transmembrane cell signaling molecules. There are 8 major classifications (1-7) of Semaphorins characterized by the existence of a conserved 500 amino acid SEMA domain at the amino terminus. Classes 3,4,6, and 7 are found in vertebrates only, whilst class 5 is found in both vertebrates and invertebrates. Each class is then divided into additional subgroups based on shared structural characteristics. Semaphorins primarily function as axon growth cone guidance factors during neuronal development. Semaphorin 3A acts as a chemo-repellent to axons, and an inhibitor of the growth of axons by signaling through receptors, Neuropilin-1and Plexin-A. Recombinant human Semaphorin 3A is a 751 amino acid protein containing the SEMA domain, an immunoglobulin c2-like domain and a basic domain (Arg/Lys rich) near the C-terminus.
氨基酸序列:
NYQNGKNNVP RLKLSYKEML ESNNVITFNG LANSSSYHTF LLDEERSRLY VGAKDHIFSF DLVNIKDFQK IVWPVSYTRR DECKWAGKDI LKECANFIKV LKAYNQTHLY ACGTGAFHPI CTYIEIGHHP EDNIFKLENS HFENGRGKSP YDPKLLTASL LIDGELYSGT AADFMGRDFA IFRTLGHHHP IRTEQHDSRW LNDPKFISAH LISESDNPED DKVYFFFREN AIDGEHSGKA THARIGQICK NDFGGHRSLV NKWTTFLKAR LICSVPGPNG IDTHFDELQD VFLMNFKDPK NPVVYGVFTT SSNIFKGSAV CMYSMSDVRR VFLGPYAHRD GPNYQWVPYQ GRVPYPRPGT CPSKTFGGFD STKDLPDDVI TFARSHPAMY NPVFPMNNRP IVIKTDVNYQ FTQIVVDRVD AEDGQYDVMF IGTDVGTVLK VVSIPKETWY DLEEVLLEEM TVFREPTAIS AMELSTKQQQ LYIGSTAGVA QLPLHRCDIY GKACAECCLA RDPYCAWDGS ACSRYFPTAK RRTRRQDIRN GDPLTHCSDL HHDNHHGHSP EERIIYGVEN SSTFLECSPK SQRALVYWQF QRRNEERKEE IRVDDHIIRT DQGLLLRSLQ QKDSGNYLCH AVEHGFIQTL LKVTLEVIDT EHLEELLHKD DDGDGSKTKE MSNSMTPSQK VWYRDFMQLI NHPNLNTMDE FCEQVWKRDR KQRRQRPGHT PGNSNKWKHL QENKKGRNRR THEFERAPRS V
来源:
CHO cells
纯度:
Greater than 95% by SDS-PAGE gel and HPLC analyses.
重组人Semaphorin 3 ARecombinant Human Semaphorin 3A
Semaphorin 3A 重组人脑信号素 3A
重组小鼠Semaphorin 4C蛋白 Recombinant Mouse Semaphorin 4C
重组人Semaphorin 蛋白 Recombinant Human Semaphorin /SEMA
重组人Semaphorin 4G蛋白 Recombinant Human Semaphorin 4G/SEMA4G
重组人Semaphorin 4B蛋白 Recombinant Human Semaphorin 4B/SEMA4B
重组人Semaphorin 3C蛋白 Recombinant Human Semaphorin 3C/SEMA3C
重组人Semaphorin 4G(Sema4G) 重组蛋白
重组小鼠Semaphorin 4A(Sema4A) 重组蛋白
重组人信号素5A(Semaphorin 5A)(Sema5A) 重组蛋白
重组人 Semaphorin 4A / SEMA4A / Semaphorin B 蛋白 (His 标签)
重组人 Semaphorin 4A / SEMA4A / Semaphorin B 蛋白 (Fc 标签)(Fc 标签)
