Pefachrome® FIXa发色底物CH3SO2-D-CHG-Gly-Arg-pNA·AcOH

Pefachrome® FIXa
Chromogenic substrate for factor IXa with improved sensitivity. Determination of factor IXa activity for in-process and quality control of factor IX preparations.
Chemical formula:  CH3SO2-D-CHG-Gly-Arg-pNA·AcOH
MW:  628.7
Kcat:  4.4 s-1                 Km:  1.3 mM
(determined in the presence of 33% ethylene glycol)
Note: The sensitivity of Pefachrome® FIXa is significantly increased in the presence of 33% ethylene glycol.

参考文献：
· Stürzebecher J, Kopetzki E, Bode W, Hopfner KP.
Dramatic enhancement of the catalytic activity of coagulation factor IXa by alcohols. FEBS Lett 1997; 412:295-300.
· Prasa D, Stürzebecher J.
Determination of activated factor IX in factor IX concentrates with a chromogenic substrate. Throm Res 1998; 92:99-102.