Recombinant Human IL-1α Peprotech厂家直销_详细资料

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生长因子此类产品包括人、小鼠或大鼠的细胞外蛋白，多数情况下可启始或影响通过细胞表面受体传递的信号。下列产品包括人、小鼠和大鼠的白细胞介素、集落刺激因子、生长因子、干扰素、脂肪因子、BMP蛋白、FGFs、TNFs、可溶性受体、细胞外结合蛋白、非抑制型丝氨酸蛋白酶抑制剂及其他免疫调节蛋白等。

Recombinant Human IL-1α Peprotech厂家直销
产品编号:
200-01A
别名:
Hematopoietin-1, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF)
描述:
IL-1α is a non-secreted, proinflammatory cytokine produced in a variety of cells, including monocytes, tissue macrophages, keratinocytes, ａnd other epithelial cells. Both IL-1α ａnd IL-1β bind to the same receptor ａnd have similar, if not identical, biological properties. These cytokines have a broad range of activities including the stimulation of thymocyte proliferation by inducing IL-2 release, B-cell maturation ａnd proliferation, mitogenic FGF-like activity ａnd the release of prostaglandin ａnd collagenase from synovial cells. However, whereas IL-1β is a secreted cytokine, IL-1α is predominantly a cell-associated cytokine. Recombinant Human IL-1α is an 18.0 kDa protein containing 159 amino acid residues.
氨基酸序列:
SAPFSFLSNV KYNFMRIIKY EFILNDALNQ SIIRANDQYL TAAALHNLDE AVKFDMGAYK SSKDDAKITV ILRISKTQLY VTAQDEDQPV LLKEMPEIPK TITGSETNLL FFWETHGTKN YFTSVAHPNL FIATKQDYWV CLAGGPPSIT DFQILENQA
来源:
E.coli
纯度:
Greater than 98% by SDS-PAGE gel ａnd HPLC analyses.
生物活性:
The ED₅₀ as determined by the dose-dependent stimulation of murine D10S cells is ≤ 0.001 ng/ml, corresponding to a specific activity of ≥ 1 x 10⁹units/mg.

交叉反应:
Cow, Monkey, Mouse, Human, Frog, Pig
研究领域:

血管生成/ 心血管癌症

糖尿病/ 体重调节免疫系统

炎症神经生物学

增殖干细胞及分化

创伤修复过敏

移植

原产国:
USA
仅用于研究。不适用于诊断或ZL。

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Recombinant Human IL-1α Peprotech厂家直销

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	血管生成/ 心血管		癌症
	糖尿病/ 体重调节		免疫系统
	炎症		神经生物学
	增殖		干细胞及分化
	创伤修复		过敏
	移植