SMA平滑肌肌动蛋白（鼠单克隆抗体）Actin,Smooth Musc...

SMA平滑肌肌动蛋白（鼠单克隆抗体）Actin,Smooth Muscle

广州健仑生物科技有限公司

微丝（microfilament，MF）又称肌动蛋白纤维，是普通存在于真核细胞中由肌动蛋白（actin）组成的直径为5~8nm的螺旋状纤维。肌动蛋白（actin）是一种中等大小的蛋白质，由375-377个氨基酸残基组成，并且是由一个大的、高度保守的基因编码。它在生物界有广泛的分布，除肌肉组织外，还存在于几乎所有的真核细胞中，如人的脑组织，血小板和多种植物细胞，在很多菌类中也有发现。

SMA是一种标记平滑肌的肌动蛋白，可以与平滑肌肌动蛋白α异构体反应，但不能识别来源于成纤维细胞、骨骼肌以及心肌的肌动蛋白。

我司还提供其它进口或国产试剂盒：登革热、疟疾、流感、A链球菌、合胞病毒、腮病毒、乙脑、寨卡、黄热病、基孔肯雅热、克锥虫病、违禁品滥用、肺炎球菌、军团菌、化妆品检测、食品安全检测等试剂盒以及日本生研细菌分型诊断血清、德国SiFin诊断血清、丹麦SSI诊断血清等产品。

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【产品介绍】

细胞定位：细胞浆

克隆号：1A4

同型：IgG/K

适用组织：石蜡/冰冻

阳性对照：阑尾

抗原修复：热修复（EDTA）

抗体孵育时间：30-60min

SMA平滑肌肌动蛋白（鼠单克隆抗体）Actin,Smooth Muscle

疾病诊断
诊断标准
WHO专家会建议的诊断原则是：
1、从新鲜粪便标本中查到吞噬有红细胞的滋养体，或从肠壁活检组织中查到滋养体是本病确诊的可靠依据。
2、从粪便标本中仅查到1-4个核包囊或肠腔型滋养体，应报告为溶组织内阿米巴、迪斯帕内阿米巴感染。此时即使患者有症状，亦不能据此得出肠阿米巴病的诊断，应根据流行病学史、血清抗体检测、粪抗原检测或PCR检测证实感染虫株确属溶组织内阿米巴后，诊断才能确立。否则必须寻找引起腹泻的其他原因。
3、在有症状患者的血清中若能查到高滴度的阿米巴抗体，亦是本病诊断的有力证据。
辅助检查
1.粪便检查：大便呈暗红色，有粪质，带血、脓或粘液，呈腥臭。
2.乙状结肠镜检查：如粪检阴性，乙状结肠镜检查有很大诊断价值。溃疡常较表浅，、覆有黄色脓液。溃疡边缘略突出，稍见充血，自溃疡面刮取材料作显微镜检查，发现病原体的机会较多。
3.阿米巴肝脓肿：腹部B超检查可见到病灶。
鉴别诊断
应与其他原因引起的肠道疾病相鉴别，尤其是细菌性痢疾，尚有肠结核、血吸虫病、结肠炎、结肠癌及其他肠道原虫感染亦可与肠阿米巴病混淆。溃疡病、胆囊病、结肠息肉等须与有不明确腹痛及肠出血者区别。综合运用以上诊断方法，鉴别不难。
疾病ZL
1、一般ZL：注意休息，进食半流质少渣高蛋白饮食。
2、病原ZL：甲硝哒唑或称灭滴灵：原是抗滴虫药物，对侵袭组织的阿米巴滋养体有极强的杀灭作用且较安全，适用于肠内肠外各型的阿米巴病。剂量为600～800mg、口服、1日3次，连服5～10日；儿童为50mg/kg/日，分3次服，连续7日。服药期间偶有抗原抗体、腹痛、头昏、心慌，不需特殊处理。服药期忌酒，因可引起精神错乱。孕妇3个月以内及哺乳妇忌用。
疾病预后
肠阿米巴病及时ZL后预后良好。如并发肠出血、肠穿孔和弥漫性腹腔炎以及有肝、肺、脑部转移性脓肿者，预后差。
疾病预防
煮沸、过滤、消毒饮水，防止吃生菜及防止饮食的被污染，适当处理粪便，防止苍蝇孳生和灭蝇，均为重要措施。检查和ZL从事饮食业的排包囊者及慢性患者极为重要。
疾病护理
1.消化道隔离。
2.病情观察：观察大便的次数和形状、颜色。
3.粪便标本的采集需要注意：及时采集新鲜大便，挑选有粘液、脓血的部分及时送检，并注意保温。

我司还提供其它进口或国产试剂盒：登革热、疟疾、流感、A链球菌、合胞病毒、腮病毒、乙脑、寨卡、黄热病、基孔肯雅热、克锥虫病、违禁品滥用、肺炎球菌、军团菌、化妆品检测、食品安全检测等试剂盒以及日本生研细菌分型诊断血清、德国SiFin诊断血清、丹麦SSI诊断血清等产品。

想了解更多的产品及服务请扫描下方二维码：

【公司名称】 广州健仑生物科技有限公司
【市场部】    杨永汉

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【腾讯  】 
【公司地址】 广州清华科技园创新基地番禺石楼镇创启路63号二期2幢101-103室

Disease diagnosis
Diagnostic criteria
The diagnostic principles that WHO experts recommend are:
1, found from the fresh stool specimens of phagocytizing red blood cell trophozoites, or from the intestinal wall biopsy found trophozoite is a reliable basis for the diagnosis of this disease.
2, only found from the stool specimens 1-4 nuclear cysts or gut trophozoites, should be reported as Entamoeba histolytica, disiphenase amoebic infection. At this point, even if the patient has symptoms, we can not conclude that the diagnosis of intestinal amoebiasis should be based on epidemiological history, serum antibody test, fecal antigen test or PCR test confirmed that infected worm indeed Entamoeba histolytica After the diagnosis can be established. Otherwise you have to look for other causes of diarrhea.
3, in patients with symptomatic sera if you can find high titers of amebic antibodies, is also a strong evidence of the diagnosis of the disease.
Auxiliary examination
1. stool examination: stool was dark red, fecal material, blood, pus or mucus, was stench.
2. sigmoidoscopy: such as fecal negative, sigmoidoscopy has great diagnostic value. More often superficial ulcers, covered with yellow pus. Ulcer slightly prominent edge, a little congestion, since the ulcer surface scrape the material for microscopic examination and found more chances of pathogens.
3. Amoeba liver abscess: Abdominal B-ultrasound can be seen lesions.
Differential diagnosis
Should be distinguished from other causes of intestinal diseases, especially bacillary dysentery, there are intestinal tuberculosis, schistosomiasis, colitis, colon cancer and other intestinal protozoa infections can also be confused with enteromoea. Canker disease, gallbladder disease, colon polyps, etc. must be with no clear abdominal pain and intestinal bleeding were the difference. Comprehensive use of the above diagnostic methods, identification is not difficult.
Disease treatment
1, the general treatment: pay attention to rest, eat less semi-liquid high protein diet.
2, the pathogen treatment: metronidazole or metronidazole: the original anti-trichomoniasis drugs, the invasion of the organization of amoeba trophozoites have a very strong role in the killing and safer, suitable for all types of intestinal Of amoebiasis. Dose 600 ~ 800mg, orally, 3 times a day, and even served 5 to 10 days; children 50mg / kg / day, 3 times for 7 consecutive days. Occasionally medication antigen antigen, abdominal pain, dizziness, palpitation, without special treatment. Take the medication bogey, because it can cause confusion. Pregnant women within 3 months and breastfeeding women hanged.
Disease prognosis
Good prognosis after timely treatment of intestinal amoebiasis. Such as complicated with intestinal bleeding, intestinal perforation and diffuse peritonitis and liver, lung, brain metastatic abscess, poor prognosis.
prevent disease
Boiling, filtration, disinfection of drinking water, to prevent eating lettuce and prevent contamination of the diet, proper disposal of manure, to prevent flies breeding and fly, are important measures. It is extremely important to examine and treat patients in the catering industry as well as chronic patients.
Disease care
1. Digestive tract isolation.
2. Disease observation: observe the number of stool and shape, color.
3. Need to pay attention to the collection of stool specimens: timely collection of fresh stool, the selection of mucus, pus and blood part of the timely submission, and pay attention to insulation.