PDCD4 Antibody (aa210-221)_详细资料

产品信息 货号： APG01204G 靶点： Human PDCD4. This antibody is expected to recognize all reported isoforms (NP_055271.2; NP_663314.1; NP_001186421.1). 应用范围： WB, IHC-P, E 宿主： Goat 数量： 100 适应物种： Human, Mouse, Rat, Rabbit, Hamster, Monkey, Chicken, Goat, Horse, Xenopus, Bovine, Guinea Pig, Dog 保存条件： Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles. 规格： 50 μg Prouduct:We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.This product is a high quality PDCD4 Antibody (aa210-221).Functiong:Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription. May play a role in apoptosis. Tumor suppressor. Inhibits tumor promoter-induced neoplastic transformation. Binds RNA (By similarity).Summary:Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription. May play a role in apoptosis. Tumor suppressor. Inhibits tumor promoter-induced neoplastic transformation. Binds RNA (By similarity).

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