分子量:
38971 Da
细胞定位:
形式:
Affinity purified antibody, Liquid
参考文献:
1. Chambers, J.K. et al. (2000) J. Biol. Chem. 275, 10767.2. Abbracchio, M.P. et al. (2003) Trends Pharmacol. Sci. 24, 52.3. Skelton, L. et al. (2003) J. Immunol. 171, 1941.
产品概述:
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.This product is a high quality P2Y14 Receptor (extracellular) antibody.
功能:
总结:
P2Y14 belongs to the P2Y receptor family that is part of the G-protein coupled receptor superfamily. To date eight functional mammalian P2Y receptors have been identified: P2Y1, P2Y2, P2Y4, P2Y6, P2Y11, P2Y12, P2Y13 and P2Y14.The P2Y receptor family mediates the effects of extracellular nucleotides such as ATP, ADP, UTP and in the case of P2Y14 UDP-glucose. UDP-glucose as the other nucleotides can be released to the extracellular milieu as the result of cell damage or by regulated non-lytic mechanisms.P2Y14 is expressed in several tissues including brain, lung and several cells of hematopoietic origin such as T lymphocytes and dendritic cells.The exact function of this receptor in the different tissues has not been clearly established but an involvement in chemotaxis, maturation of immature dendritic cells and neuroimmune regulation has been suggested.Abgent is pleased to offer a highly specific antibody directed against a conserved epitope in the second extracellular loop of the human P2Y14 receptor. Anti-P2Y14 (extracellular) antibody (#AG1064) can be used in Western blot analysis, and will recognize human and mouse samples.
联系方式:
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