PGR antibody - N-terminal region | LBP62777 | Leading Biology

商品分类：多克隆抗体

产品概述：The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Progesterone receptor isoform B (PRB) is involved activation of c-SRC/MAPK signaling on hormone stimulation. Isoform 4: Increases mitochondrial membrane potential and cellular respiration upon stimulation by progesterone.

来源：Rabbit

存储溶液：Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

参考文献：Kastner P.,et al.EMBO J. 9:1603-1614(1990).Misrahi M.,et al.Biochem. Biophys. Res. Commun. 143:740-748(1987).Kieback D.G.,et al.Submitted (JUL-1997) to the EMBL/GenBank/DDBJ databases.Hisatomi H.,et al.Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases.Chen C.,et al.Mol. Phylogenet. Evol. 47:637-649(2008).

特异性：Human

别名：Progesterone receptor, PR, Nuclear receptor subfamily 3 group C member 3, PGR, NR3C3

简单描述：Rabbit Polyclonal PGR antibody - N-terminal region. Validated for use in WB.

详情：FunctionThe steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Progesterone receptor isoform B (PRB) is involved activation of c-SRC/MAPK signaling on hormone stimulation. Isoform 4: Increases mitochondrial membrane potential and cellular respiration upon stimulation by progesterone.Cellular_LocationNucleus. Cytoplasm. Note=Nucleoplasmic shuttling is both homone- and cell cycle-dependent. On hormone stimulation, retained in the cytoplasm in the G(1) and G(2)/M phases Isoform 4: Mitochondrion outer membrane

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