商品分类：多克隆抗体
产品概述：Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B-cells and the B-cell response.
靶点/蛋白：A C-terminal peptide corresponding to amino acids 254-269 of human BLyS.
来源：Rabbit
参考文献：Shu H.-B.,et al.J. Leukoc. Biol. 65:680-683(1999).Schneider P.,et al.J. Exp. Med. 189:1747-1756(1999).Moore P.A.,et al.Science 285:260-263(1999).Gavin A.L.,et al.J. Biol. Chem. 278:38220-38228(2003).Lahiri A.,et al.J. Autoimmun. 39:189-198(2012).
特异性：Human, Mouse
别名：Tumor necrosis factor ligand superfamily member 13B, B lymphocyte stimulator, BLyS, B-cell-activating factor, BAFF, Dendritic cell-derived TNF-like molecule, TNF- and APOL-related leukocyte expressed ligand 1, TALL-1, CD257, Tumor necrosis factor ligand superfamily member 13b, membrane form, Tumor necrosis factor ligand superfamily member 13b, soluble form, TNFSF13B, BAFF, BLYS, TALL1, TNFSF20, ZTNF4
应用：IHC-P (10 μg/ml), WB (0.5-2 μg/ml),
简单描述：Rabbit Polyclonal BAFF Antibody (aa254-269). Validated for use in WB, IHC-P.
详情：FunctionCytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B-cells and the B-cell response.Cellular_LocationCell membrane; Single-pass type II membrane proteinTissue_LocationAbundantly expressed in peripheral blood Leukocytes and is specifically expressed in monocytes and macrophages. Also found in the spleen, lymph node, bone marrow, T- cells and dendritic cells. A lower expression seen in placenta, heart, lung, fetal liver, thymus, and pancreas. Isoform 2 is expressed in many myeloid cell lines
生物商城：http://www.annoron.com
办公电话：010-56256916
官方售后：400-965-8633
企业 QQ：3212874516、3198592576
地 址：北京大兴经济技术开发区(亦庄)同济中路7号兴盛国际A栋4层
温馨提示：不可用于临床ZL。
BAFF Antibody (aa254-269) | LBP60555 | Leading Biology
