HSPB1 / HSP27 Antibody (aa1-205, clone 2A5) | LM12240 | Leading Biology

商品分类：单克隆抗体

产品概述：Involved in stress resistance and actin organization.

来源：Mouse

参考文献：Hickey E.,et al.Nucleic Acids Res. 14:4127-4145(1986).Carper S.W.,et al.Nucleic Acids Res. 18:6457-6457(1990).Hino M.,et al.Biochem. Biophys. Res. Commun. 271:164-169(2000).Briolay J.,et al.Submitted (JUN-1993) to the EMBL/GenBank/DDBJ databases.Yu W.,et al.Genome Res. 7:353-358(1997).

特异性：Human

别名：Heat shock protein beta-1, HspB1, 28 kDa heat shock protein, Estrogen-regulated 24 kDa protein, Heat shock 27 kDa protein, HSP 27, Stress-responsive protein 27, SRP27, HSPB1, HSP27, HSP28

应用：IHC-P (10 μg/ml), WB (1:1000-1:2000),

简单描述：Mouse Monoclonal HSPB1 / HSP27 Antibody (aa1-205, clone 2A5). Validated for use in WB, IHC-P, E. Clone: 2A5.

详情：FunctionInvolved in stress resistance and actin organization.Cellular_LocationCytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle. Note=Cytoplasmic in interphase cells. Colocalizes with mitotic spindles in mitotic cells. Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing specklesTissue_LocationDetected in all tissues tested: skeletal muscle, heart, aorta, large intestine, small intestine, stomach, esophagus, bladder, adrenal gland, thyroid, pancreas, testis, adipose tissue, kidney, liver, spleen, cerebral cortex, blood serum and cerebrospinal fluid. Highest levels are found in the heart and in tissues composed of striated and smooth muscle

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