CD70 / TNFSF7 (Activated T- & B-Lymphocyte Marker) Antibody - Without BSA and Azide | LM10486 | Leading Biology

商品分类：单克隆抗体

产品概述：It recognizes a protein of 30kDa, identified as CD70. It is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T- and B-lymphocytes. It induces proliferation of co-stimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin synthesis.

来源：Mouse

参考文献：Lens, S.M., et al. 1995. CD27-CD70 interaction: unravelling its implication in normal and neoplastic B cell growth. Leuk. Lymphoma 18: 51-59

特异性：Human

别名：CD70 antigen, CD27 ligand, CD27-L, Tumor necrosis factor ligand superfamily member 7, CD70, CD70, CD27L, CD27LG, TNFSF7

简单描述：Mouse Monoclonal CD70 / TNFSF7 (Activated T- & B-Lymphocyte Marker) Antibody - Without BSA and Azide. Validated for use in IHC-F, IF, FC, E, IP. Clone: TNFS7/1026.

详情：FunctionCytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells.Cellular_LocationMembrane; Single-pass type II membrane protein

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